Basic Information

IDDRAMP01123
SequenceILGPVISTIGGVLGGLLKNL
Length20
NameMaximin-H1 (Toads, amphibians, animals)
SourceBombina maxima (Giant fire-bellied toad) (Chinese red belly toad)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.11835991] Gram-negative bacterium: Escherichia coli ATCC 25922 (MIC=9 μg/ml);##Gram-positive bacteria: Staphylococcus aureus ATCC 2592 (MIC=4.5 μg/ml), Bacillus pyocyaneus CMCCB 1010 (MIC=9 μg/ml).##Yeast: Candida albicans ATCC 2002 (MIC=4.5 μg/ml).
Hemolytic Activity[Ref:11835991]90–100% hemolytic activity at 50 μg/ml against rabbit red blood cells
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P83080, P83081, Q58T74, Q58T41
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15770703, 11835991

Physicochemical Properties

Residues20
SequenceILGPVISTIGGVLGGLLKNL
Molecular Weight1934.366
Grand Average of Hydropathy1.42
Isoelectric Point8.75
Charge at pH 7.40.555
Secondary StructureHelix: 0.500, Turn: 0.400, Sheet: 0.250
Instability Index36.855
Aromaticity0

Similar Structure Search

Candidates based on structure

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