Basic Information

IDDRAMP01152
SequenceGVIDAAKKVVNVLKNLP
Length17
NameUperin-3.6 (toads, amphibians, animals)
SourceUperoleia mjobergii (Australian toadlet)
ActivityAntimicrobial, Antibacterial, Anti-Gram+
PathogenGram-positive bacteria: Bacillus cereus (MIC=25 µg/ml), Lactococcus lactis (MIC=3 µg/ml), Listeria innocua (MIC=50 µg/ml), Micrococcus luteus (MIC=25 µg/ml), Staphylococcus aureus (MIC=25 µg/ml), Staphylococcus epidermidis (MIC=12.5 µg/ml), Streptococcus uberis (MIC=12.5 µg/ml).(Ref.2)
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot P82043
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID10461748, 15203252

Physicochemical Properties

Residues17
SequenceGVIDAAKKVVNVLKNLP
Molecular Weight1778.144
Grand Average of Hydropathy0.488
Isoelectric Point9.703
Charge at pH 7.41.55
Secondary StructureHelix: 0.412, Turn: 0.235, Sheet: 0.235
Instability Index10.753
Aromaticity0

Similar Structure Search

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