Basic Information

IDDRAMP20797
SequenceGVIDAAKKVVNVLKNLF
Length17
NameUperin 3.6 (Toad, amphibians, animals)
SourceUperoleia mjobergii (Australian toadlet)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.10461748] Gram positive bacteria: Bacillus cereus (MIC=25 μg/ml), Leuconostoc lactis (MIC=3 μg/ml), Listeria innocua (MIC=50 μg/ml), Micrococcus luteus (MIC=50 μg/ml), Staphylococcus aureus (MIC=25 μg/ml), Staphylococcus epidermidis (MIC=12 μg/ml), Streptococcus uberis (MIC=12 μg/ml);##Gram-negative bacterium: Pasteurella haemolytica (MIC=25 μg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.10461748] No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot P82043
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID10461748

Physicochemical Properties

Residues17
SequenceGVIDAAKKVVNVLKNLF
Molecular Weight1828.203
Grand Average of Hydropathy0.747
Isoelectric Point9.703
Charge at pH 7.41.55
Secondary StructureHelix: 0.471, Turn: 0.176, Sheet: 0.235
Instability Index-0.576
Aromaticity0.059

Similar Structure Search

Candidates based on structure

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