Basic Information
| ID | DRAMP01170 |
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| Sequence | NLVSGLIEARKYLEQLHRKLKNCKV |
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| Length | 25 |
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| Name | Distinctin 2 (Frogs, amphibians, animals) |
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| Source | Phyllomedusa distincta (Tree frog) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | Note: Distinctin chain 2 links to Distinctin chain 1 to form a heterodimeric peptide to exert antibacterial function. ##Gram-positive bacteria: Enterococcus faecalis (MIC=14.5 µM), Staphylococcus aureus (MIC=28.0 µM);##Gram-negative bacteria: Pseudomonas aeruginosa (MIC=28.0 µM), Escherichia coli (MIC=14.5 µM). |
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| Hemolytic Activity | No hemolysis information or data found in the reference(s) presented in this entry |
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| Cytotoxicity | No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Free |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
|
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| PDB |
1XKM resolved by NMR |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 11297740 |
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