Basic Information

IDDRAMP01201
SequenceAAPRGGKGFFCKLFKDC
Length17
NameSchmackerin-C1 (Frogs, amphibians, animals)
SourceOdorrana schmackeri
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacteria: Escherichia coli ATCC 25922 (MIC=100 µg/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=50 µg/ml); ##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=50 µg/ml).##Yeast: Candida albicans ATCC 2002 (MIC=100 µg/ml).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys11 and Cys17)
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID22029824

Physicochemical Properties

Residues17
SequenceAAPRGGKGFFCKLFKDC
Molecular Weight1845.195
Grand Average of Hydropathy-0.1
Isoelectric Point9.39
Charge at pH 7.42.552
Secondary StructureHelix: 0.235, Turn: 0.235, Sheet: 0.176
Instability Index-5.253
Aromaticity0.176

Similar Structure Search

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