Basic Information

IDDRAMP01246
SequenceFGLPMLSILPKALCILLKRKC
Length21
NameJaponicin-2 (Frogs, amphibians, animals)
SourceRana japonica (Japanese brown frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacterium: Escherichia coli (MIC=12 µM);##Gram-positive bacterium: Staphylococcus aureus (MIC=20 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys14 and Cys21)
Linear/Cyclic/BranchedCyclic
Uniprot P83306
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID11835990

Physicochemical Properties

Residues21
SequenceFGLPMLSILPKALCILLKRKC
Molecular Weight2358.071
Grand Average of Hydropathy1.081
Isoelectric Point9.851
Charge at pH 7.43.501
Secondary StructureHelix: 0.429, Turn: 0.190, Sheet: 0.381
Instability Index54.1
Aromaticity0.048

Similar Structure Search

Candidates based on structure

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