Basic Information
| ID | DRAMP01249 |
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| Sequence | FLIGMTQGLICLITRKC |
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| Length | 17 |
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| Name | Dybowskin-2 (Frogs, amphibians, animals) |
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| Source | Rana dybowskii (Korea brown frog) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | [Ref.17698251]Gram-positive bacteria: Micrococcus luteus ATCC4698 (MIC=6.25 µg/ml), Staphylococcus aureus KCTC3881 (MIC=15 µg/ml), Bacillus subtilis ATCC6633 (MIC=25 µg/ml), Staphylococcus epidermidis ATCC12228 (MIC=25 µg/ml);##Gram-negative bacteria: Shigella dysenteriae ATCC9752 (MIC=50 µg/ml), Escherichia coli KCTC2433 (MIC=60 µg/ml), Klebsiella pneumoniae ATCC10031 (MIC=60 µg/ml), Proteus mirabilis ATCC25933 (MIC>100 µg/ml);##Yeast: Candida albicans ATCC36232 (MIC=100 µg/ml). |
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| Hemolytic Activity | [Ref:17698251] It has 10.99% hemolytic activity at 100 μg/ml against human red blood cells |
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| Cytotoxicity | No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Cyclization (Cys11 and Cys17) |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 17698251 |
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