Basic Information

IDDRAMP02813
SequenceFHPSLWVLIPQYIQLIRKILKSG
Length23
NameConolysin-Mt1
SourceConus mustelinus (Weasel cone)
ActivityAntimicrobial, Antibacterial, Anti-Gram+
Pathogen[Ref.17927208]Gram-positive bacterium: Staphylococcus aureus (MIC=25-50 µM);##Gram-positive bacterium: Escherichia coli (MIC>50 µM).
Hemolytic Activity[Ref.17927208]95% hemolytic activity at 25 μM against human red blood cells
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P0C8S6
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID17927208

Physicochemical Properties

Residues23
SequenceFHPSLWVLIPQYIQLIRKILKSG
Molecular Weight2750.328
Grand Average of Hydropathy0.448
Isoelectric Point10.29
Charge at pH 7.42.587
Secondary StructureHelix: 0.522, Turn: 0.217, Sheet: 0.174
Instability Index28.126
Aromaticity0.13

Similar Structure Search

Candidates based on structure

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