Basic Information

IDDRAMP21242
SequenceFIFHIIKGLFHAGKMI
Length16
NameEpinecidin-8 (Derived from Epinecidin)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.23598079] Gram-positive bacteria : Staphylococcus aureus(MIC=6.25 mg/L), Staphylococcus sp.(MIC=12.5 mg/L);##Gram-negative bacteria : Grouper Vibrio alginolyticus(MIC=12.5 mg/L), Vibrio harveyi(MIC=6.25 mg/L)
Hemolytic Activity[Ref.23598079] 0% hemolysis at 50 mg/L , 10% hemolysis at 100 mg/L , 20% hemolysis at 200 mg/L , 50% hemolysis at 400 mg/L against sheep red blood cells
Cytotoxicity[Ref.23598079] No cytotoxicity information found.
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID23598079

Physicochemical Properties

Residues16
SequenceFIFHIIKGLFHAGKMI
Molecular Weight1872.324
Grand Average of Hydropathy1.181
Isoelectric Point10.003
Charge at pH 7.41.626
Secondary StructureHelix: 0.500, Turn: 0.125, Sheet: 0.188
Instability Index41.294
Aromaticity0.188

Similar Structure Search

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