Basic Information

IDDRAMP18396
SequenceFFWHHIGHALDAAKRVHGMLSG
Length22
NamemoroNC-NH2 (moronecidin-like peptide; fish, animals)
SourceNotothenia coriiceps
ActivityAntimicrobial, Antibacterial, Antifungal
PathogenActive against Gram- S. sonnei (ATCC 29930) (MIC 12.5 uM), Psychrobacter sp. (PAMC 25501) (MIC 5 uM), E. coli DH5alpha (MIC 12.5 uM), Gram+ S. pyogenes (ATCC 19615) (MIC 25 uM), S. aureus (ATCC 33591) (MIC 25 uM) , L. monocytogenes (ATCC 15313) (MIC 12.5 uM), and yeast C. tropicalis (ATCC 20115) (MIC 5 uM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID28122029

Physicochemical Properties

Residues22
SequenceFFWHHIGHALDAAKRVHGMLSG
Molecular Weight2487.84
Grand Average of Hydropathy0.073
Isoelectric Point8.775
Charge at pH 7.40.702
Secondary StructureHelix: 0.318, Turn: 0.182, Sheet: 0.273
Instability Index50.386
Aromaticity0.136

Similar Structure Search

Candidates based on structure

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