Basic Information

IDDRAMP01164
SequenceGIGALSAKGALKGLAKGLAEHFAN
Length24
NameBombinin (toads, amphibians, animals)
SourceBombina variegata (Yellow-bellied toad)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
Pathogen[Ref.8223491]Gram-negative bacterium: Escherichia coli D21 (MIC=3 µM);##Gram-positive bacterium: Staphylococcus aureus Cowan 1 (MIC=14 µM).
Hemolytic Activity[Ref.8223491] The lethal concentration (LC, the lowest concentration that inhibits growth) was over 50 μM
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot P01505
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed IDPubMed ID is not available, 8223491

Physicochemical Properties

Residues24
SequenceGIGALSAKGALKGLAKGLAEHFAN
Molecular Weight2294.651
Grand Average of Hydropathy0.358
Isoelectric Point9.703
Charge at pH 7.41.588
Secondary StructureHelix: 0.250, Turn: 0.292, Sheet: 0.458
Instability Index-22.642
Aromaticity0.042

Similar Structure Search

Candidates based on structure

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