Basic Information

IDDRAMP21159
SequenceGIMISLMKKLAAHIAK
Length16
NameHYL-5 (Derived from HYL)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC=43 μM), Staphylococcus epidermidis(MIC=8.8 μM);##Gram-negative bacteria : Escherichia coli(MIC=12 μM), Pseudomonas aeruginosa 5482(MIC=47 μM);##Fungi : Candida albicans(MIC=12 μM)
Hemolytic Activity[Ref.26998557] LC50=320 μM against human red blood cells
Cytotoxicity[Ref.26998557] No cytotoxicity information found.
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID26998557

Physicochemical Properties

Residues16
SequenceGIMISLMKKLAAHIAK
Molecular Weight1725.214
Grand Average of Hydropathy0.888
Isoelectric Point10.302
Charge at pH 7.42.587
Secondary StructureHelix: 0.312, Turn: 0.125, Sheet: 0.438
Instability Index20.919
Aromaticity0

Similar Structure Search

Candidates based on structure

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