Basic Information

IDDRAMP21158
SequenceGIMSSLMKKLKKHIAK
Length16
NameHYL-4 (Derived from HYL)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC>100 μM), Staphylococcus epidermidis(MIC=10 μM);##Gram-negative bacteria : Escherichia coli(MIC=26 μM), Pseudomonas aeruginosa 5482(MIC=6.4 μM);##Fungi : Candida albicans(MIC=12 μM)
Hemolytic Activity[Ref.26998557] LC50>400 μM against human red blood cells
Cytotoxicity[Ref.26998557] No cytotoxicity information found.
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID26998557

Physicochemical Properties

Residues16
SequenceGIMSSLMKKLKKHIAK
Molecular Weight1813.322
Grand Average of Hydropathy-0.156
Isoelectric Point10.602
Charge at pH 7.44.582
Secondary StructureHelix: 0.250, Turn: 0.188, Sheet: 0.312
Instability Index60.419
Aromaticity0

Similar Structure Search

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