Basic Information

IDDRAMP21155
SequenceGIMSSLMKKLKAHIAK
Length16
NameHYL-1 (Derived from HYL)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC>100 μM), Staphylococcus epidermidis(MIC=16 μM);##Gram-negative bacteria : Escherichia coli(MIC=30 μM), Pseudomonas aeruginosa 5482(MIC=26 μM);##Fungi : Candida albicans(MIC=23 μM)
Hemolytic Activity[Ref.26998557] LC50>400 μM against human red blood cells
Cytotoxicity[Ref.26998557] No cytotoxicity information found.
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID26998557

Physicochemical Properties

Residues16
SequenceGIMSSLMKKLKAHIAK
Molecular Weight1756.228
Grand Average of Hydropathy0.2
Isoelectric Point10.478
Charge at pH 7.43.584
Secondary StructureHelix: 0.250, Turn: 0.188, Sheet: 0.375
Instability Index55.112
Aromaticity0

Similar Structure Search

Candidates based on structure

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