| ID | DRAMP21160 |
|---|---|
| Sequence | GIMSSLMKKLAAIIAK |
| Length | 16 |
| Name | HYL-6 (Derived from HYL) |
| Source | Synthetic construct |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
| Pathogen | [Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC=7.2 μM), Staphylococcus epidermidis(MIC=5 μM);##Gram-negative bacteria : Escherichia coli(MIC=3.6 μM), Pseudomonas aeruginosa 5482(MIC=8 μM);##Fungi : Candida albicans(MIC=8.4 μM) |
| Hemolytic Activity | [Ref.26998557] LC50=93 μM against human red blood cells |
| Cytotoxicity | [Ref.26998557] No cytotoxicity information found. |
| N-terminal Modification | Free |
| C-terminal Modification | Amidation |
| Linear/Cyclic/Branched | Linear |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 26998557 |
Physicochemical Properties
| Residues | 16 |
|---|---|
| Sequence | GIMSSLMKKLAAIIAK |
| Molecular Weight | 1675.152 |
| Grand Average of Hydropathy | 1.038 |
| Isoelectric Point | 10.302 |
| Charge at pH 7.4 | 2.55 |
| Secondary Structure | Helix: 0.312, Turn: 0.188, Sheet: 0.438 |
| Instability Index | 38.262 |
| Aromaticity | 0 |