Basic Information

IDDRAMP21162
SequenceGIMSSLMKKLKKIIAK
Length16
NameHYL-8 (Derived from HYL)
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.26998557] Gram-positive bacteria : Staphylococcus aureus 6271(MIC=32 μM), Staphylococcus epidermidis(MIC=1.9 μM);##Gram-negative bacteria : Escherichia coli(MIC=9 μM), Pseudomonas aeruginosa 5482(MIC=5 μM);##Fungi : Candida albicans(MIC=5.2 μM)
Hemolytic Activity[Ref.26998557] LC50>400 μM against human red blood cells
Cytotoxicity[Ref.26998557] No cytotoxicity information found.
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID26998557

Physicochemical Properties

Residues16
SequenceGIMSSLMKKLKKIIAK
Molecular Weight1789.341
Grand Average of Hydropathy0.325
Isoelectric Point10.602
Charge at pH 7.44.545
Secondary StructureHelix: 0.312, Turn: 0.188, Sheet: 0.312
Instability Index27.65
Aromaticity0

Similar Structure Search

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