Basic Information

IDDRAMP01306
SequenceFLSLIPHAINAVSAIAKHF
Length19
NamePhylloseptin-7 (PS-7; Frogs, amphibians, animals)
SourcePhyllomedusa azurea (Orange-legged monkey frog) (Phyllomedusa hypochondrialis azurea)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacterium: Escherichia coli ATCC 11775 (MIC=7.2 µM);##Gram-positive bacteria: Staphylococcus aureus ATCC 12600 (MIC=3.6 µM), Micrococcus luteus ATCC 49732 (MIC=1.8 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.16963159]No cytotoxicity information found##[Ref.17553595]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot P85882
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID17553595, 16963159

Physicochemical Properties

Residues19
SequenceFLSLIPHAINAVSAIAKHF
Molecular Weight2049.417
Grand Average of Hydropathy1.111
Isoelectric Point8.764
Charge at pH 7.40.628
Secondary StructureHelix: 0.421, Turn: 0.211, Sheet: 0.316
Instability Index2.5
Aromaticity0.105

Similar Structure Search

Candidates based on structure

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