Basic Information

IDDRAMP01346
SequenceVIGSILGALASGLPTLISWIKNR
Length23
NamePrepromelittin-related peptide (Frogs, amphibians, animals)
SourceRana sakuraii (Japanese brown frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacterium: Escherichia coli (MIC=25 µM);##Gram-positive bacterium: Staphylococcus aureus (MIC=6 µM).##Yeast: Candida albicans (MIC=25 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.17174009]No cytotoxicity information found##[Ref.17826868]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot A7BJK5
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID17174009, 17826868

Physicochemical Properties

Residues23
SequenceVIGSILGALASGLPTLISWIKNR
Molecular Weight2379.838
Grand Average of Hydropathy0.97
Isoelectric Point11.001
Charge at pH 7.41.521
Secondary StructureHelix: 0.435, Turn: 0.348, Sheet: 0.261
Instability Index18.93
Aromaticity0.043

Similar Structure Search

Candidates based on structure

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