Basic Information

IDDRAMP01350
SequenceFCTMIPIPRCY
Length11
NameTigerinin-1 (Frogs, amphibians, animals)
SourceRana tigerina (Indian bull frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-positive bacteria: Bacillus subtilis (MIC=30 µg/ml), Staphylococcus aureus ATCC 8530 (MIC=30 µg/ml), Micrococcus luteus MT 166 (MIC=20 µg/ml);##Gram-negative bacteria: Escherichia coli (MIC=40 µg/ml), Pseudomonas putida NCIM 2102 (MIC=40 µg/ml).##Fungi: Saccharomyces cerevisiae ATCC 8530 (MIC=80 µg/ml).
Hemolytic Activity[Ref.11031261] It exhibits no hemolytic activity up to a concentration of 200 μg/ml against rat erythrocytes.
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedCyclic
Uniprot P82651
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID11031261

Physicochemical Properties

Residues11
SequenceFCTMIPIPRCY
Molecular Weight1343.679
Grand Average of Hydropathy0.818
Isoelectric Point8.058
Charge at pH 7.40.506
Secondary StructureHelix: 0.364, Turn: 0.182, Sheet: 0.091
Instability Index26.636
Aromaticity0.182

Similar Structure Search

Candidates based on structure

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