Basic Information

IDDRAMP01352
SequenceRVCYAIPLPICY
Length12
NameTigerinin-3 (Frogs, amphibians, animals)
SourceRana tigerina (Indian bull frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-positive bacteria: Bacillus subtilis (MIC=30 µg/ml), Staphylococcus aureus ATCC 8530 (MIC=30 µg/ml), Micrococcus luteus MT 166 (MIC=30 µg/ml);##Gram-negative bacteria: Escherichia coli (MIC=40 µg/ml), Pseudomonas putida NCIM 2102 (MIC=40 µg/ml).##Fungi: Saccharomyces cerevisiae ATCC 8530 (MIC=80 µg/ml).
Hemolytic Activity[Ref.11031261] It exhibits no hemolytic activity up to a concentration of 200 μg/ml against rat erythrocytes.
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedCyclic
Uniprot P82653
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID11031261

Physicochemical Properties

Residues12
SequenceRVCYAIPLPICY
Molecular Weight1410.745
Grand Average of Hydropathy1.125
Isoelectric Point8.045
Charge at pH 7.40.503
Secondary StructureHelix: 0.500, Turn: 0.167, Sheet: 0.167
Instability Index42.55
Aromaticity0.167

Similar Structure Search

Candidates based on structure

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