Basic Information

IDDRAMP01377
SequenceFMPILSCSRFKRC
Length13
NameOdorranain-G1 (OdG1; Frogs, amphibians, animals)
SourceOdorrana grahami (Yunnanfu frog) (Rana grahami)
ActivityAntimicrobial, Antibacterial, Antifungal, Anti-Gram+, Anti-Gram-
Pathogen[Ref.17272268] Gram-negative bacterium: Escherichia coli (MIC=4.68 μg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=9.37 μg/ml), Bacillus subtilis (MIC=37.5 μg/ml).##Yeast: Candida albicans (MIC=1.10 μg/ml).
Hemolytic Activity[Ref:17272268] It has no hemolytic activity against rabbit red blood cells
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys7 and Cys13)
Linear/Cyclic/BranchedCyclic
Uniprot A6MBL7, A6MBL8
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID17272268

Physicochemical Properties

Residues13
SequenceFMPILSCSRFKRC
Molecular Weight1587.973
Grand Average of Hydropathy0.362
Isoelectric Point9.696
Charge at pH 7.42.506
Secondary StructureHelix: 0.308, Turn: 0.231, Sheet: 0.154
Instability Index111.254
Aromaticity0.154

Similar Structure Search

Candidates based on structure

Address: No.2699 Qianjin Street, Changchun City, China. Zip Code: 130012. 苏ICP备2021057230号-1.