Basic Information

IDDRAMP01413
SequenceGLLGSIFGAGKKIACALSGLC
Length21
NameNigrocin-2HSb (Frogs, amphibians, animals)
SourceOdorrana hosii (Hose's rock frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=28 µM);##Gram-negative bacterium: Escherichia coli ATCC 25726 (MIC=14 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys15 and Cys21)
Linear/Cyclic/BranchedCyclic
Uniprot P0C8U1
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID18621071

Physicochemical Properties

Residues21
SequenceGLLGSIFGAGKKIACALSGLC
Molecular Weight1979.41
Grand Average of Hydropathy1.238
Isoelectric Point8.904
Charge at pH 7.41.503
Secondary StructureHelix: 0.333, Turn: 0.333, Sheet: 0.333
Instability Index18.319
Aromaticity0.048

Similar Structure Search

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