Basic Information

IDDRAMP01443
SequenceGILSNVLGMGKKIVCGLSGLC
Length21
NameNigrocin-2SCc (Frogs, amphibians, animals)
SourceOdorrana schmackeri (Chinese Odorrana frogs)
ActivityAntimicrobial, Antibacterial, Anti-Gram-
PathogenGram-negative bacterium: Escherichia coli (MIC=70 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys15 and Cys21)
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID20158520

Physicochemical Properties

Residues21
SequenceGILSNVLGMGKKIVCGLSGLC
Molecular Weight2062.563
Grand Average of Hydropathy1.171
Isoelectric Point8.904
Charge at pH 7.41.503
Secondary StructureHelix: 0.381, Turn: 0.381, Sheet: 0.238
Instability Index2.524
Aromaticity0

Similar Structure Search

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