Basic Information
| ID | DRAMP01438 |
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| Sequence | GIFGKILGAGKKVLCGLSGLC |
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| Length | 21 |
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| Name | Nigrocin-2JDa (Frogs, amphibians, animals) |
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| Source | Odorrana jingdongensis (Jingdong frog) (Rana jingdongensis) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | [Ref.22917879]Gram-positive bacteria: Staphylococcus aureus ATCC 25923 (MIC=16 µM), Staphylococcus aureus CIB 85462 (MIC=8 µM);##Gram-negative bacteria: Escherichia coli ATCC 25992 (MIC=16 µM), Escherichia coli CIB 84492 (MIC=16 µM);##Yeast: Candida albicans (MIC=63 µM). |
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| Hemolytic Activity | [Ref:22917879] It has 80.3 ± 5.5% hemolytic activity at 128 μg/ml against rabbit red blood cells |
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| Cytotoxicity | No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Cyclization (Cys15 and Cys21) |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
B3A0M6 |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 22917879 |
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