Basic Information

IDDRAMP03831
SequenceGLWNSIKIAGKKLFVNVLDKIRCKVAGGC
Length29
NamePalustrin-2ISb-des-C7
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacterium: Escherichia coli (MIC=6.3 µM);##Gram-positive bacteria: Staphylococcus aureus (MIC=1.6 µM), S. aureus (MRSA) (MIC=12.5 µM).##Yeast: Candida albicans (MIC=100 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization(Cys23 and Cys29).
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID21911019

Physicochemical Properties

Residues29
SequenceGLWNSIKIAGKKLFVNVLDKIRCKVAGGC
Molecular Weight3131.801
Grand Average of Hydropathy0.383
Isoelectric Point9.902
Charge at pH 7.44.496
Secondary StructureHelix: 0.379, Turn: 0.241, Sheet: 0.172
Instability Index5.838
Aromaticity0.069

Similar Structure Search

Candidates based on structure

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