Basic Information

IDDRAMP03833
SequenceGLWNSIKIAGKNLFVNVLDKIRCKVAGGC
Length29
NamePalustrin-2ISb-des-C7-12N
SourceSynthetic construct
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacterium: Escherichia coli (MIC=12.5 µM);##Gram-positive bacteria: Staphylococcus aureus (MIC=3.1 µM), S. aureus (MRSA) (MIC=12.5 µM);##yeast Candida albicans (MIC=100 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization(Cys23 and Cys29).
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID21911019

Physicochemical Properties

Residues29
SequenceGLWNSIKIAGKNLFVNVLDKIRCKVAGGC
Molecular Weight3117.732
Grand Average of Hydropathy0.397
Isoelectric Point9.699
Charge at pH 7.43.499
Secondary StructureHelix: 0.379, Turn: 0.276, Sheet: 0.172
Instability Index8.766
Aromaticity0.069

Similar Structure Search

Candidates based on structure

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