Basic Information

IDDRAMP01547
SequenceSLWETIKNAGKGFILNILDKIRCKVAGGCKT
Length31
NameNigroain-K2 (Frogs, amphibians, animals)
SourceRana nigrovittata (Black-striped frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Antifungal
Pathogen[Ref.19778602]Gram-positive bacteria: Staphylococcus aureus ATCC25923 (MIC=11.25 µg/ml), Staphylococcus aureus ATCC43300 (MIC=9.38 µg/ml), Bacillus subtilis (MIC=9.38 µg/ml);##Gram-positive bacteria: Escherichia coli ML-35P (MIC=25.00 µg/ml), Pseudomonas aeruginosa PA01 (MIC=25.00 µg/ml), Pseudomonas aeruginosa ATCC27853 (MIC=25.00 µg/ml);##Yeast: Candida albicans ATCC2002 (MIC=15.00 µg/ml)
Hemolytic Activity[Ref:19778602]85.52 ± 3.26% hemolytic activity at 50 µg/ml against rabbit red cells
Cytotoxicity[Ref.19778602]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationFree
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID19778602

Physicochemical Properties

Residues31
SequenceSLWETIKNAGKGFILNILDKIRCKVAGGCKT
Molecular Weight3378.019
Grand Average of Hydropathy0.074
Isoelectric Point9.592
Charge at pH 7.43.193
Secondary StructureHelix: 0.323, Turn: 0.226, Sheet: 0.194
Instability Index31.465
Aromaticity0.065

Similar Structure Search

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