Basic Information

IDDRAMP02242
SequenceGLMDVFKGAAKNLLASALDKIRCKVTKC
Length28
NameRanatuerin-2PRa (frogs, amphibians, animals)
SourceRana pirica (Hokkaido frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.15003829] Gram-negative bacterium: Escherichia coli(MIC=13μM);## Gram-positive bacterium: Staphylococcus aureus(MIC>100μM);## Yeast: Candida albicans(MIC=100μM)
Hemolytic Activity[Ref.15003829] HC50=150μM against human erythrocytes
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys23 and Cys28)
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15003829

Physicochemical Properties

Residues28
SequenceGLMDVFKGAAKNLLASALDKIRCKVTKC
Molecular Weight2994.641
Grand Average of Hydropathy0.293
Isoelectric Point9.594
Charge at pH 7.43.497
Secondary StructureHelix: 0.286, Turn: 0.143, Sheet: 0.321
Instability Index-13.918
Aromaticity0.036

Similar Structure Search

Candidates based on structure

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