Basic Information

IDDRAMP01237
SequenceGFMDTAKNVAKNVAVTLLDKLKCKITGGC
Length29
NamePalustrin-2ISa (Frogs, amphibians, animals)
SourceOdorrana ishikawae
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacterium: Escherichia coli (MIC=100 µM);##Gram-positive bacteria: Staphylococcus aureus (MIC=25 µM), Staphylococcus aureus (MRSA) (MIC=100 µM), Bacillus subtilis (MIC=12.5 µM).##Yeast: Candida albicans (MIC=100 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys23 and Cys29)
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID21193000

Physicochemical Properties

Residues29
SequenceGFMDTAKNVAKNVAVTLLDKLKCKITGGC
Molecular Weight3039.635
Grand Average of Hydropathy0.234
Isoelectric Point9.243
Charge at pH 7.42.497
Secondary StructureHelix: 0.276, Turn: 0.172, Sheet: 0.241
Instability Index-8.838
Aromaticity0.034

Similar Structure Search

Candidates based on structure

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