Basic Information

IDDRAMP01397
SequenceGFMDTAKNVAKNMAVTLLDNLKCKITKAC
Length29
NameOdorranain-F-OA2 (Frogs, amphibians, animals)
SourceOdorrana grahami (Yunnanfu frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.22029824]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=7.5 µg/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=7.5 µg/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=3.8 µg/ml);##Yeast: Candida albicans ATCC 2002 (MIC=3.8 µg/ml).
Hemolytic Activity[Ref:22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 μg/mL.
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys23 and Cys29)
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID22029824

Physicochemical Properties

Residues29
SequenceGFMDTAKNVAKNMAVTLLDNLKCKITKAC
Molecular Weight3142.778
Grand Average of Hydropathy0.124
Isoelectric Point9.243
Charge at pH 7.42.497
Secondary StructureHelix: 0.241, Turn: 0.138, Sheet: 0.310
Instability Index15.097
Aromaticity0.034

Similar Structure Search

Candidates based on structure

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