Basic Information

IDDRAMP01232
SequenceGFMDTAKNVAKNVAATLLDKLKCKITGGC
Length29
NamePalustrin-2ISc (Frogs, amphibians, animals)
SourceOdorrana ishikawae (Ishikawa's frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacterium: Escherichia coli (MIC=100 µM);##Gram-positive bacteria: Staphylococcus aureus (MIC=25 µM), Bacillus subtilis (MIC=12.5 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys23 and Cys29)
Linear/Cyclic/BranchedCyclic
Uniprot G3XHN9
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID21867685

Physicochemical Properties

Residues29
SequenceGFMDTAKNVAKNVAATLLDKLKCKITGGC
Molecular Weight3011.582
Grand Average of Hydropathy0.152
Isoelectric Point9.243
Charge at pH 7.42.497
Secondary StructureHelix: 0.241, Turn: 0.172, Sheet: 0.276
Instability Index-5.91
Aromaticity0.034

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