Basic Information

IDDRAMP01401
SequenceGFMNTAKNVAKNVAVTLLDNLKCKITGGC
Length29
NameOdorranain-F-OW1 (Frogs, amphibians, animals)
SourceOdorrana wuchuanensis (Chinese odorous frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacteria: Escherichia coli (MIC=2 µM), Pseudomonas aeruginosa (MIC=4 µM);##Gram-positive bacterium: Staphylococcus aureus (MIC=4 µM).##Yeast: Candida albicans ATCC 2002 (MIC=2 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys23 and Cys29)
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID22029824

Physicochemical Properties

Residues29
SequenceGFMNTAKNVAKNVAVTLLDNLKCKITGGC
Molecular Weight3024.581
Grand Average of Hydropathy0.248
Isoelectric Point9.308
Charge at pH 7.42.499
Secondary StructureHelix: 0.276, Turn: 0.241, Sheet: 0.241
Instability Index-0.728
Aromaticity0.034

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