Basic Information

IDDRAMP01376
SequenceGFMDTAKNAAKNVAVTLLDNLKCKITKAC
Length29
NameOdorranain-F1 (OdF1; Frogs, amphibians, animals)
SourceOdorrana grahami (Yunnanfu frog) (Rana grahami)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.17272268] Gram-negative bacterium: Escherichia coli (MIC=4.20 μg/ml);##Gram-positive bacteria: Staphylococcus aureus (MIC=2.10 μg/ml), Bacillus subtilis (MIC=8.40 μg/ml).##Yeast: Candida albicans (MIC=1.05 μg/ml).
Hemolytic Activity[Ref.17272268] RCH=15.4 ± 3.5% against rabbit red blood cells at 50 μg/ml. RCH, red cell hemolysis.
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys23 and Cys29)
Linear/Cyclic/BranchedCyclic
Uniprot A6MBL3
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID17272268

Physicochemical Properties

Residues29
SequenceGFMDTAKNAAKNVAVTLLDNLKCKITKAC
Molecular Weight3082.66
Grand Average of Hydropathy0.121
Isoelectric Point9.243
Charge at pH 7.42.497
Secondary StructureHelix: 0.241, Turn: 0.138, Sheet: 0.310
Instability Index10.841
Aromaticity0.034

Similar Structure Search

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