Basic Information

IDDRAMP01396
SequenceGFMDTAKNVAKNMAGNLLDNLKCKITKAC
Length29
NameOdorranain-F-OA1 (Frogs, amphibians, animals)
SourceOdorrana grahami (Yunnanfu frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.22029824]Gram-negative bacteria: Escherichia coli ATCC 25922 (MIC=5 µg/ml), Bacillus pyocyaneus CMCCB 10104 (MIC=10 µg/ml);##Gram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=2.5 µg/ml);##Yeast: Candida albicans ATCC 2002 (MIC=2.5 µg/ml).
Hemolytic Activity[Ref:22029824] It shows no hemolytic activity against human red blood cells at the concentration of 50 μg/mL.
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys23 and Cys29)
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID22029824

Physicochemical Properties

Residues29
SequenceGFMDTAKNVAKNMAGNLLDNLKCKITKAC
Molecular Weight3113.697
Grand Average of Hydropathy-0.131
Isoelectric Point9.243
Charge at pH 7.42.497
Secondary StructureHelix: 0.207, Turn: 0.207, Sheet: 0.310
Instability Index15.097
Aromaticity0.034

Similar Structure Search

Candidates based on structure

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