Basic Information
| ID | DRAMP01445 |
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| Sequence | GLLSKVLGVGKKVLCGVSGLC |
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| Length | 21 |
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| Name | Nigrocin-2 (Nigrocin-2LVa; Frogs, amphibians, animals) |
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| Source | Rana nigromaculata (Black-spotted frog) |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal |
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| Pathogen | [Ref.11682065]Gram-positive bacterium: Micrococcus luteus(MIC=2.5μg/ml);##Gram-negative bacteria: Shigella dysenteriae(MIC=10μg/ml), Klebsiella pneumoniae(MIC=10μg/ml), Pseudomonas aeruginosa(MIC=100μg/ml), Salmonella typhimurium(MIC=22.5μg/ml), Proteus mirabilis(MIC>200μg/ml), Serratia marcescens(MIC>200μg/ml);##Yeast: Candida albicans(MIC=150μg/ml). |
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| Hemolytic Activity | [Ref:11682065] It has 0.9% hemolytic activity at 100μg/ml against human red blood cells |
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| Cytotoxicity | No cytotoxicity information found |
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| N-terminal Modification | Free |
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| C-terminal Modification | Cyclization (Cys15 and Cys21) |
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| Linear/Cyclic/Branched | Cyclic |
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| Uniprot |
P0C009 |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 11682065 |
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