Basic Information

IDDRAMP01702
SequenceGLWSTIKNVGKEAAIAAGKAVLGSL
Length25
NameDermaseptin-H5 (Dermaseptin-like peptide 5, DMS5; Frogs, amphibians, animals)
SourcePhyllomedusa azurea (Orange-legged monkey frog) (Phyllomedusa hypochondrialis azurea)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-negative bacterium: Escherichia coliEscherichia coli ATCC 11775 (MIC=0.5 µM);##Gram-positive bacteria: Staphylococcus aureus ATCC 12600 (MIC=0.5 µM), Micrococcus luteus ATCC 49732 (MIC=2.0 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.17553595]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot Q1EJP4
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID17553595

Physicochemical Properties

Residues25
SequenceGLWSTIKNVGKEAAIAAGKAVLGSL
Molecular Weight2454.862
Grand Average of Hydropathy0.572
Isoelectric Point9.703
Charge at pH 7.41.551
Secondary StructureHelix: 0.320, Turn: 0.280, Sheet: 0.360
Instability Index5.488
Aromaticity0.04

Similar Structure Search

Candidates based on structure

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