Basic Information

IDDRAMP01412
SequenceGLLGSLFGAGKKVACALSGLC
Length21
NameNigrocin-2HSa (Frogs, amphibians, animals)
SourceOdorrana hosii (Hose's rock frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacterium: Staphylococcus aureus ATCC 25923 (MIC=56 µM);##Gram-negative bacterium: Escherichia coli ATCC 25726 (MIC=28 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys15 and Cys21)
Linear/Cyclic/BranchedCyclic
Uniprot P0C8U0
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID18621071

Physicochemical Properties

Residues21
SequenceGLLGSLFGAGKKVACALSGLC
Molecular Weight1965.383
Grand Average of Hydropathy1.19
Isoelectric Point8.904
Charge at pH 7.41.503
Secondary StructureHelix: 0.333, Turn: 0.333, Sheet: 0.381
Instability Index18.319
Aromaticity0.048

Similar Structure Search

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