Basic Information

IDDRAMP01675
SequenceGLFKTLIKGAGKMLGHVAKQFLGSQGQPES
Length30
NameDermaseptin-3 (DStar 03; Frogs, amphibians, animals)
SourcePhyllomedusa tarsius (Brownbelly leaf frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Antifungal
Pathogen[Swiss_Prot Entry P84923]Gram-positive bacteria: Staphylococcus aureus, Enterococcus faecalis;##Gram-neagtive bacterium: Pseudomonas aeruginosa;##Fungi: Candida albicans and Paracoccidioides brasiliensis.
Hemolytic Activity[Ref:PubMed ID is not available]100% hemolytic activity at 128 µg/ml
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P84923
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed IDPubMed ID is not available

Physicochemical Properties

Residues30
SequenceGLFKTLIKGAGKMLGHVAKQFLGSQGQPES
Molecular Weight3128.645
Grand Average of Hydropathy-0.137
Isoelectric Point10.001
Charge at pH 7.42.585
Secondary StructureHelix: 0.267, Turn: 0.300, Sheet: 0.267
Instability Index34.623
Aromaticity0.067

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