Basic Information

IDDRAMP01409
SequenceGILSGILGVGKKLVCGLSGLC
Length21
NameNigrocin-OR1 (Frogs, amphibians, animals)
SourceOdorrana rotodora (Chinese odorous frogs)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
PathogenGram-negative bacteria: Escherichia coli (MIC=4 µM), Pseudomonas aeruginosa (MIC=7 µM);##Gram-positive bacterium: Staphylococcus aureus (MIC=2 µM).##Yeast: Candida albicans (MIC=4 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys15 and Cys21)
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID22029824

Physicochemical Properties

Residues21
SequenceGILSGILGVGKKLVCGLSGLC
Molecular Weight1987.473
Grand Average of Hydropathy1.41
Isoelectric Point8.904
Charge at pH 7.41.503
Secondary StructureHelix: 0.429, Turn: 0.381, Sheet: 0.238
Instability Index7.652
Aromaticity0

Similar Structure Search

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