Basic Information

IDDRAMP01440
SequenceGILSGILGMGKKLVCGLSGLC
Length21
NameNigrocin-2LVb (Frogs, amphibians, animals)
SourceOdorrana livida (Chinese Odorrana frogs)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-
PathogenGram-positive bacterium: Staphylococcus aureus (MIC=50 µM);##Gram-negative bacterium: Escherichia coli (MIC=15 µM).
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys15 and Cys21)
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID20158520

Physicochemical Properties

Residues21
SequenceGILSGILGMGKKLVCGLSGLC
Molecular Weight2019.538
Grand Average of Hydropathy1.3
Isoelectric Point8.904
Charge at pH 7.41.503
Secondary StructureHelix: 0.381, Turn: 0.381, Sheet: 0.286
Instability Index11.695
Aromaticity0

Similar Structure Search

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