Basic Information

IDDRAMP01419
SequenceGLLSGILGAGKNIVCGLSGLC
Length21
NameNigrocin-2GRc (Frogs, amphibians, animals)
SourceRana grahami (Asian frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram-
Pathogen[Ref.16621155]Gram-negative bacterium: Escherichia coli (MIC=50 µM).
Hemolytic Activity[Ref:16621155] LC50>500 μM against human erythrocytes
CytotoxicityNo cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationCyclization (Cys15 and Cys21)
Linear/Cyclic/BranchedCyclic
Uniprot
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID16621155

Physicochemical Properties

Residues21
SequenceGLLSGILGAGKNIVCGLSGLC
Molecular Weight1945.351
Grand Average of Hydropathy1.314
Isoelectric Point8.058
Charge at pH 7.40.506
Secondary StructureHelix: 0.381, Turn: 0.429, Sheet: 0.286
Instability Index23.448
Aromaticity0

Similar Structure Search

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