Basic Information

IDDRAMP01594
SequenceGLFDIIKKVASVVGGL
Length16
NameCitropin-1.2 (Frogs, amphibians, animals)
SourceLitoria citropa (Australian blue mountains tree frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+
PathogenGram-positive bacteria: Bacillus cereus (MIC=25 µg/ml), Leuconostoc lactis (MIC=3 µg/ml), Listeria innocua (MIC=100 µg/ml), Micrococcus luteus (MIC=12 µg/ml), Staphylococcus aureus (MIC=25 µg/ml), Staphylococcus epidermidis (MIC=25 µg/ml), Streptococcus uberis (MIC=12 µg/ml). (Ref.2)
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.15203252]No cytotoxicity information found##[Ref.10504394]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot P81840, P81841, P81842, P81843
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID10504394, 15203252

Physicochemical Properties

Residues16
SequenceGLFDIIKKVASVVGGL
Molecular Weight1615.954
Grand Average of Hydropathy1.281
Isoelectric Point8.591
Charge at pH 7.40.553
Secondary StructureHelix: 0.500, Turn: 0.250, Sheet: 0.188
Instability Index8.881
Aromaticity0.062

Similar Structure Search

Candidates based on structure

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