Basic Information

IDDRAMP01612
SequenceGLFDIVKKVVGAFGSL
Length16
NameAurein-2.5 (Frogs, amphibians, animals)
SourceLitoria raniformis (Southern bell frog); also Litoria aurea (Green; also golden bell frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-cancer
Pathogen[Ref.10951191]Gram-positive bacteria: Bacillus cereus (MIC=50 μg/ml), Leuconostoc lactis (MIC=12 μg/ml), Listeria innocua (MIC=50 μg/ml), Micrococcus luteus (MIC=100 μg/ml), Staphylococcus epidermidis (MIC=100 μg/ml), Staphylococcus aureus (MIC=50 μg/ml)
Hemolytic ActivityNo hemolysis information or data found in the reference(s) presented in this entry
Cytotoxicity[Ref.10951191]No cytotoxicity information found
N-terminal ModificationFree
C-terminal ModificationAmidation
Linear/Cyclic/BranchedLinear
Uniprot P69018, P69019, P82392
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID10951191, 15203252

Physicochemical Properties

Residues16
SequenceGLFDIVKKVVGAFGSL
Molecular Weight1649.97
Grand Average of Hydropathy1.175
Isoelectric Point8.591
Charge at pH 7.40.553
Secondary StructureHelix: 0.500, Turn: 0.250, Sheet: 0.188
Instability Index-5.938
Aromaticity0.125

Similar Structure Search

Candidates based on structure

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