Basic Information

IDDRAMP01847
SequenceGFKDLLKGAAKALVKTVLF
Length19
NameAscaphin-8 (Frogs, amphibians, animals)
SourceAscaphus truei (Coastal tailed frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antiviral
Pathogen[Ref.15207717]Gram-negative bacterium: Escherichia coli (MIC=6 µM);##Gram-positive bacterium: Staphylococcus aureus (MIC=6 µM).
Hemolytic Activity[Ref.15207717]HC50=50 μM against human erythrocytes
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot P0CJ32
PDB
3D View
PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15207717

Physicochemical Properties

Residues19
SequenceGFKDLLKGAAKALVKTVLF
Molecular Weight2019.472
Grand Average of Hydropathy0.737
Isoelectric Point10.001
Charge at pH 7.42.548
Secondary StructureHelix: 0.421, Turn: 0.105, Sheet: 0.368
Instability Index-13.358
Aromaticity0.105

Similar Structure Search

Candidates based on structure

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