ABPDB

Basic Information

ID	DRAMP29101
Sequence	GFKDLLKGAAKALVKAVLF
Length	19
Name	Ascaphin-8 [T16A]
Source	Synthetic construct
Activity	Antimicrobial, Antibacterial,Anti-Gram+, Anti-Gram-, Anti-cancer, Antifungal
Pathogen	[Ref.18554256]Gram-negative bacteria:Escherichia coli ATCC 25726(MIC=6 µM);##Gram-positive bactria:Staphylococcus aureus ATCC 25923(MIC=3 µM);##Fungi:Candida albicans ATCC 900280(MIC=6 µM).##Cancer:human hepatoma‐derived cells HepG2 (LC50=9 µM).
Hemolytic Activity	[Ref.18554256]Hemolysis against human erythrocytes (LC50=22 µM).
Cytotoxicity	[Ref.18554256]Cytotoxicity:Mouse fibroblasts L929 (LC50=5 µM).
N-terminal Modification	Free
C-terminal Modification	Amidation
Linear/Cyclic/Branched	Linear
Uniprot	P0CJ32
PDB
3D View
PDB Download	Download PDB Predicted by Alphafold2
PubMed ID	18554256

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