| ID | DRAMP18661 |
|---|---|
| Sequence | GWLDVAKKIGKAAFNVAKNFL |
| Length | 21 |
| Name | Ctx-Ha (Frogs, amphibians, animals) |
| Source | Hypsiboas albopunctatus |
| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anitifungal, Anti-Gram- |
| Pathogen | [Ref.22391524]Gram-positive bacterium: Staphylococcus aureus (MIC=1.7 μmol/L; MMC=6.8 μmol/L);##Gram-negative bacterium: Escherichia coli (MIC=3.4 μmol/L; MMC=3.4 μmol/L);##Fungi: Candida albicans (MIC=54.6 μmol/L; MMC<100 μmol/L) |
| Hemolytic Activity | [Ref.22391524]HC50=37.3±1.4 μmol/L against human red blood cells |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 22391524 |
Physicochemical Properties
| Residues | 21 |
|---|---|
| Sequence | GWLDVAKKIGKAAFNVAKNFL |
| Molecular Weight | 2290.704 |
| Grand Average of Hydropathy | 0.262 |
| Isoelectric Point | 10.001 |
| Charge at pH 7.4 | 2.548 |
| Secondary Structure | Helix: 0.381, Turn: 0.190, Sheet: 0.286 |
| Instability Index | 6.033 |
| Aromaticity | 0.143 |