Basic Information
| ID | DRAMP21201 |
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| Sequence | GIGKFLHSAKKWGKAFVGEIMNS |
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| Length | 23 |
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| Name | Magainin 2a (M2a; Frogs, Amphibians, Animals) |
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| Source | From frog |
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| Activity | Antimicrobial, Antibacterial, Anti-Gram+, Anti-Gram- |
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| Pathogen | [Ref.18586467] Gram-positive bacteria : Staphylococcus aureus (BCRC 10780)(MIC=128 μg/ml), Staphylococcus xylosus (BCRC 12930)(MIC=128 μg/ml), Staphylococcus aureus (BCRC 10781)(MIC=128 μg/ml), Listeria monocytogenes (BCRC 14845)(MIC=128 μg/ml), Streptococcus bovis (BCRC 14729)(MIC=128 μg/ml), Streptococcus iniae (laboratory strain)(MIC=128 μg/ml), Lactococcus garvieae (laboratory strain)(MIC=32 μg/ml);##Gram-negative bacteria : Klebsiella oxytoca (BCRC 13985)(MIC=64 μg/ml), Pseudomonas aeruginosa (BCRC 10944)(MIC=64 μg/ml), Escherichia coli (BCRC 10675)(MIC=64 μg/ml), Enterobacter aerogenes (BCRC 10370)(MIC=128 μg/ml), Enterobacter cloacae (BCRC 10401)(MIC=32 μg/ml), Yersinia enterocolitica (BCRC 13999)(MIC=128 μg/ml) |
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| Hemolytic Activity | [Ref.18586467] MHC=128 μM against human red blood cells |
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| Cytotoxicity | [Ref.18586467] No cytotoxicity information found. |
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| N-terminal Modification | Free |
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| C-terminal Modification | Free |
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| Linear/Cyclic/Branched | Linear |
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| Uniprot |
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| PDB |
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| 3D View | |
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| PDB Download | Download PDB Predicted by Alphafold2 |
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| PubMed ID | 18586467 |
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