| ID | dbAMP17722 |
|---|---|
| Sequence | GIGKFIHAAKKFGKLFIGEIMNS |
| Length | 23 |
| Name | Magainin-2 [L6I][S8A][A15L][V17I]&&I6A8L15I17-M2a |
| Source | |
| Activity | Antibacterial |
| Pathogen | Staphylococcus aureus (MIC=9.6µM)&&RBCs Source of Human (EC50 =32µM)&&RBCs Source of Human (98% hemolysis at 150µM)&&Pseudomonas aeruginosa (MIC=19-28µM)&&Escherichia coli (MIC=2.4µM) |
| Hemolytic Activity | Not included yet |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 9166783, 9166783 |
Physicochemical Properties
| Residues | 23 |
|---|---|
| Sequence | GIGKFIHAAKKFGKLFIGEIMNS |
| Molecular Weight | 2507.004 |
| Grand Average of Hydropathy | 0.326 |
| Isoelectric Point | 10.001 |
| Charge at pH 7.4 | 2.585 |
| Secondary Structure | Helix: 0.348, Turn: 0.261, Sheet: 0.217 |
| Instability Index | 5.261 |
| Aromaticity | 0.13 |