| ID | dbAMP17585 |
|---|---|
| Sequence | GLGKFLHSAKRFGKAFVGEAMNS |
| Length | 23 |
| Name | Magainin-2 [I2L][K11R][I20A]&&L2R11A20-M2a |
| Source | |
| Activity | Antibacterial |
| Pathogen | Staphylococcus aureus (MIC=>75µM)&&RBCs Source of Human (EC50 >1000µM)&&RBCs Source of Human (12% hemolysis at 150µM)&&Pseudomonas aeruginosa (MIC=>75µM)&&Escherichia coli (MIC=75µM) |
| Hemolytic Activity | Not included yet |
| Cytotoxicity | Not included yet |
| N-terminal Modification | Not included yet |
| C-terminal Modification | Not included yet |
| Linear/Cyclic/Branched | Not included yet |
| Uniprot | |
| PDB | |
| 3D View | |
| PDB Download | Download PDB Predicted by Alphafold2 |
| PubMed ID | 9166783, 9166783 |
Physicochemical Properties
| Residues | 23 |
|---|---|
| Sequence | GLGKFLHSAKRFGKAFVGEAMNS |
| Molecular Weight | 2452.831 |
| Grand Average of Hydropathy | -0.091 |
| Isoelectric Point | 10.29 |
| Charge at pH 7.4 | 2.588 |
| Secondary Structure | Helix: 0.261, Turn: 0.304, Sheet: 0.304 |
| Instability Index | 9.387 |
| Aromaticity | 0.13 |