Basic Information

IDDRAMP01873
SequenceGIWDTIKSMGKVFAGKILQNL
Length21
NameBrevinin-2-related peptide (Frogs, amphibians, animals)
SourceRana septentrionalis (mink frog)
ActivityAntimicrobial, Antibacterial, Anti-Gram+, Anti-Gram-, Antifungal
Pathogen[Ref.15556063]Gram-negative bacterium: Escherichia coli (MIC=13 µM);##Gram-positive bacterium: Staphylococcus aureus (MIC=25 µM);##Yeast: Candida albicans (MIC=70 µM).
Hemolytic Activity[Ref.15556063]HC50=70 µM against human erythrocytes
CytotoxicityNot included yet
N-terminal ModificationNot included yet
C-terminal ModificationNot included yet
Linear/Cyclic/BranchedNot included yet
Uniprot
PDB
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PDB DownloadDownload PDB Predicted by Alphafold2
PubMed ID15556063

Physicochemical Properties

Residues21
SequenceGIWDTIKSMGKVFAGKILQNL
Molecular Weight2319.763
Grand Average of Hydropathy0.286
Isoelectric Point9.703
Charge at pH 7.41.55
Secondary StructureHelix: 0.381, Turn: 0.238, Sheet: 0.190
Instability Index2.805
Aromaticity0.095

Similar Structure Search

Candidates based on structure

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